Showing posts with label mary louise smith. Show all posts
Showing posts with label mary louise smith. Show all posts

Sunday, November 25, 2012

Meet the DOCTOR MOM who brought us wartime penicillin when it could do us some good, not 5 years after the war ended

MAE SMITH
Her name is Mary Louise (Pelliter Becker) Smith,  but she was much better know as Mrs Mae Smith or Mrs John L Smith.


That was because Mary Louise Smith was what her eldest daughter, born 1918 in New Jersey, was called by all.

Or rather, had been called by all.

Mary Louise junior was at the family summer home in Stonington Connecticut sometime in the 1930s when she contracted spinal meningitis and quickly died in theNew London Connecticut hospital.

There was effective treatments for some of the various forms of meningitis in the 1930s that reduced the death total from 100% down to still very high levels from between 50% to 25% .

Serum worked on two forms of the disease but required repeated highly skilled injections into the spinal cord area - sulfa which came along in the late 1930s, had a similar success rate.

But if the root cause was the pneumonia bacteria, the death rate remained at 100%.

Penicillin reduced that to between 50% to 30% and penicillin had been found to be extremely effective on pneumonia bacteria as far  back as the Fall of 1928, by Alexander Fleming.

But he didn't believe it would work by injection - despite never having tried to see if what he believed was actually factual.

His laziness was needlessly fatal for millions - in particular for his own brother and for Mary Louise Smith.

Dawson's passion got to Doctor Mom


Dr Martin Henry Dawson always was plain spoken - he believed from the start that natural penicillin at the state of development it was in the Fall of 1928 (or the Fall of 1940 or 1943) was more than good enough ready to save lives .

If we only had enough penicillin from the drug companies, he'd say, we could start saving these children dying needlessly of diseases like spinal meningitis and endocarditis.

Now Mary Louise junior's father , John L Smith, was a charitable man but an exceedingly cautious man --- but  he was also senior enough at the 'fine chemicals' firm where he worked, to it do his bidding if he wished.

I firmly believe that once his wife, Mae, picked up the essence of Dawson's sermonette, she never let up on her husband to move forward as fast as morally possible on making lots of penicillin.

'Our daughter is dead but there is no need for us to sit back and watch our frinds' daughters die needlessly'.

Mae was John L's moral compass and she was like a bloodhound on this issue.

Eventually her pleadings and the sight of enough dying baby girls, moved even the cautious John L.

And when he did decide to move, he moved fast and he moved hard.

In five short months his firm was producing almost more natural penicillin than the world knew what to do with it : penicillin and Pfizer never looked back.

All thanks to a tragedy, an impassioned doctor and Doctor Mom.....

Tuesday, September 7, 2010

Mae Smith ; the real life DOCTOR MOM that gave us penicillin

Readers sometimes asked me if DOCTOR MOM was a real person.

I usually say "No, Dawson was trying to reach all the Doctor Moms in America , via his success in preventing all the deaths and all the worries caused by childhood Rheumatic Fever."

But I have reflected and maybe my readers are right - yes, there was was one specific Doctor Mom that Dawson reached - perhaps, indeed, only one that he reached.

But one can be more than enough.

Her real name was Mae Smith, though she is sometimes known as Mrs John l Smith or ,more accurately, as Mary Louise Smith.

MAE SMITH in 1954
Her husband owned 25% of the Brooklyn Dodgers baseball team and after his death, she held those shares.

More books have been written on these , the original "Boys of Summer", than any other team.

Many people seem to rate the day the team left Brooklyn as more significant in the decline of America than Watergate or Viet Nam.

The other Mary Louise Smith is also very important in this story : she was the Smiths' daughter.

John L grew up in a small seaport in Connecticut and he loved to sail more than almost anything and he loved his cottage in his old home town.

One day when the family was out in the cottage, far from big cities and big city high tech hospitals, young Mary Louise said she had a stiff neck. And a headache. And a fever. And that in fact, she generally wasn't feeling very good indeed.

That put her family in a real panic.

Not as much as it did the local doctors - it was obviously Spinal Meningitis - still a deadly, every-minute-counts-disease even today with antibiotics.

By the time they got her to a big hospital, it was too late to even stabilize her - though surviving a late case of spinal meningitis can be a very mixed blessing - it often leaves you physically and mentally challenged.

An immediate (and I mean like yesterday) massive needle full of Penicillin was the best cure then , as it still is today.

Penicillin had been discovered at the time of Mary Louise II's death, but had not yet been produced, let alone mass produced.

In 1941 and 1942 and in 1943, as Dawson always naggingly reminded any and all visitors from John L.'s firm, it still was not being mass produced.

"But if it had been developed back then and if it was a staple in the black bag of even the smallest backwoods doctor, Mary Louise would be alive today."

"How many more Mary Louises would have to die needlessly before the world got enough penicillin to make a difference?"

And on and on.

John L had heard this all too many times before - he felt that Dawson simply didn't understand the technical and economic issues that prevented his firm from taking the plunge.

"What risk ", said Dawson , "are you not planning to take the company public, and to do a stock split?  This war has made you guys even richer - give something back to the fighting man - and the fighting woman."

I bet John L would go home at night, get a stiff drink and unwind at his wife, all about what a nag that Henry Dawson was -- "why he even said this and he dared say that."

I don't think John L bought Dawson's line.

But to her credit, I think Mrs John L eventually did.

I bet, late at night, just when John L was trying to get some shuteye , she would softly bring up the question of 'why couldn't the firm take a little risk for once, do something extra for the war effort?'

I think it must have rubbed off eventually, because if his firm was cautious, John L was even more so.

But between late August 1943 till March 1944, that 'stiff little man' was like a man possessed, so determined was he to get a big new, NATURAL, penicillin plant on line as soon as possible.

(This was just at the very time that the Florey team at Oxford University were semi-secretly announcing that they had totally synthesised penicillin chemically and that to continue to rely on natural production by the mold was a 'retrograde' step - so John L was betting against the received opinion.)

But they went ahead anyway: shifts of crews building around the clock, lit by Klieg Lights and posters everywhere reminding employees that this was a "Race Against Death."

 "The quicker this building is done, the quicker penicillin can go out to the wounded boys at the front."

It paid off  because by D-Day Pfizer, his firm, was producing most of the world's penicillin---and the company has never looked back.

We never did get any of that wonderful 'Refined Penicillin' out of the chappies at Oxford - but 'Brooklyn Crude' pulled us through the war anyway.

And I like to think a lot of the credit for starting Pfizer on the road to becoming the world's biggest company should go to a quiet but persistent push from  "Doc" Mae Smith.....